The U.S. Food and Drug Administration (FDA) has received reports linking certain serious and painful skin diseases to Dipeptidyl peptidase (DPP-4) inhibitors, including:
The onset of these reactions typically occurred within the first three months of the initiation of treatment.
Sometimes they occur after the first dose.
Despite numerous reports of serious and painful skin diseases, the FDA has only required a label change to include the risk of Bullous Pemphigoid.
Each of the individuals reported having Bullous Pemphigoid resulted in a serious outcome, with half requiring hospitalization and one resulting in death, according to the FDA.
Bullous Pemphigoid is a rare skin disorder that causes rashes and blistering.
Symptoms of the condition include:
A physician or dermatologist diagnoses Pemphigoid by performing a biopsy of the affected area.
DPP-4 inhibitors are medications that, when used in combination with diet and exercise, can lower blood sugar in adults suffering from type 2 diabetes.
The FDA approved the first DPP-4 inhibitor, Januvia, in 2006.
DPP-4 inhibitors work in an entirely different way than other diabetes medications, which inhibit an enzyme in the gut that breaks down the hormones that help lower blood glucose.
DPP-4 inhibitors inactivate hormones called incretins in the gut, promoting higher levels of incretins to keep blood glucose in the normal range, particularly after meals.
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Camp Lejeune’s water contamination issue spanned several decades starting in the 1950s. Exposure to these chemicals has been linked to various serious health issues, including cancer, organ diseases, and death.
Research is increasingly suggesting a link between the use of Tylenol during pregnancy and the development of neurodevelopmental disorders, such as autism and ADHD, in infants.
Legal action is being taken against manufacturers of Aqueous Film-Forming Foam (AFFF), a chemical used in fighting fires. The plaintiffs allege that exposure to the foam caused health issues such as cancer, organ damage, and birth and fertility issues.
Here, at TruLaw, we’re committed to helping victims get the justice they deserve.
Alongside our partner law firms, we have successfully collected over $3 Billion in verdicts and settlements on behalf of injured individuals.
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512 cases (2,048 trays) of Gordon Food Service (GFS) Sienna Bakery® Chocolate Decadent Brownies (GFS#226240) and Sienna Bakery® Chocolate Peanut Butter Brownies have been recalled by Dianne’s Fine Desserts due to a mislabeling and undeclared peanut, according to the FDA. Consumers who are allergic or
According to the FDA, Baxter Healthcare Corporation’s September 21, 2023 recall of its Novum IQ Syringe Pump is now identified as Class I, the most serious type, because use of the device has been found to put users at risk of serious injuries or death.
Publix Supermarkets, Inc., of Lakeland, Florida, has voluntarily recalled certain batches of private-label Egg Custard Pie sold between October 20, 2023 and November 16, 2023 because they may contain coconut, an allergen not listed on the product’s ingredient statement. Officials say the affected packages, which