DPP-4 Inhibitors

A popular class of type 2 diabetes drugs referred to as Dipeptidyl peptidase (DPP-4)  inhibitors may cause users to develop painful skin conditions and have been linked to painful skin injuries such as:

 Bullous Pemphigoid

 Erythema multiforme

Drug eruption

Toxic skin eruption

Stevens-Johnson syndrome


Oculomucocutaneous syndrome

The FDA has  reports of the above skin diseases and additional skin symptoms that appear to be linked to DPP-4 inhibitors, but as of today, the FDA has only required a label change to include the risk of bullous pemphigoid.

Instant Case Decision

See if you qualify for a Diabetes Drug (DPP-4) Skin Condition Lawsuit and the right to potentially significant financial recovery.

The Diabetes Drug / Skin COndition Instant Case Evaluator provides lawsuit qualification information and details regarding your situation.

1. Did you take diabetes medication?

2. Did you then develop skin injuriy or complications?

See If You Qualify

FDA Safety Labeling Change added a new warning for “Bullous Pemphigoid” which is a rare skin disorder that results in skin rashes and blistering on the legs, arms and abdomen. Pemphigoid can also cause blistering on the mucous membranes. Mucous membranes produce mucous that helps protect the inside of the body such as eyes, nose, mouth and genitals.

DDP-4 Inhibitors include:

Januvia Janumet Janumet XR
Onglyza Kombiglyze Tradjenta
Nesina Glyxambi Jentadueto
Kazano Oseni Sitagliptin / Metformin

According to a December 2016 FDA, DPP-4 inhibitors used to treat diabetes mellitus type 2 were found to cause Bullous Pemphigoid in several individuals. For this reason, the FDA sent out label change requirements to the manufacturers of these drugs. According to the FDA, each of the reported injured individuals had very serious outcomes, half of them required hospitalization and one died.

Symptoms and Characteristics of a Pemphigoid Diagnosis:

Blistering that occurs on the arms, legs, abdomen and mucous membranes

Red rash develops before the blisters

Blisters are large and filled with fluid that is usually clear, but may contain some blood

The blisters are thick and do not rupture easily

The skin around the blisters may appear normal or slightly red or dark

Ruptured blisters are usually sensitive and painful

Hives and itching

bullous pemphigoid blisters and skin rash

How do I know if My Blisters are Pemphigoid?

The diagnosis of Pemphigoid needs to be made by your doctor or dermatologist, and they may need to perform a biopsy, removing small samples of the skin from the affected area, in order to do so. If patients see symptoms listed below, the FDA is directing them to discontinue the DPP-4 medication and go see a dermatologist for diagnosis and appropriate treatment.
If you are experiencing a skin irritation/complication, please consider reporting it to the FDA and let us know so that the public is made aware of the risks.

Should You File a Diabetes Drug Lawsuit To Protect Your Legal Rights?

Did you take DPP-4 Diabetes Medication?





Other Diabetes Medication

Were you diagnosed with a skin disease or did you experience side effects?

Bullous Pemphigoid

Stevens-Johnson Syndrome

Blistering / Rash


Other Diagnosis or Complications

If you answered yes to these two questions you should look into your legal rights. Fill out our Secure Diabetes Drug Skin Condition Instant Case Evaluation if you believe you may need to protect your legal rights.

Contact Us For a Diabetes Drug / Skin Complication Case Analysis!

Secure, No cost/No obligation Analysis of Your Pemphigoid Lawsuit

Additional Information
View Report
Receive instant case analysis upon submission of this form.