Attorney Jessica Paluch-Hoerman, founder of TruLaw, has over 28 years of experience as a personal injury and mass tort attorney, and previously worked as an international tax attorney at Deloitte. Jessie collaborates with attorneys nationwide — enabling her to share reliable, up-to-date legal information with our readers.
This article has been written and reviewed for legal accuracy and clarity by the team of writers and legal experts at TruLaw and is as accurate as possible. This content should not be taken as legal advice from an attorney. If you would like to learn more about our owner and experienced injury lawyer, Jessie Paluch, you can do so here.
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The Depo-Provera lawsuit involves allegations against Pfizer, the manufacturer of Depo-Provera, a contraceptive injection linked to the development of brain tumors (meningiomas).
These lawsuits claim that Pfizer failed to adequately warn patients and healthcare providers about the potential risks associated with long-term medication use.
On this page, we’ll provide an overview of the Depo-Provera lawsuit symptoms, the connection between Depo-Provera and meningiomas, common symptoms reported in the Depo-Provera MDL, and much more.
At the heart of the Depo-Provera MDL are allegations that Pfizer knew or should have known about the link between Depo-Provera and meningiomas but failed to provide sufficient warnings.
Scientific studies have supported this connection, showing that long-term use of Depo-Provera can increase the risk of developing meningiomas.
If you have been diagnosed with a meningioma after using Depo-Provera, you may be eligible to file a lawsuit.
At TruLaw, attorney Jessica Paluch-Hoerman specializes in handling complex product liability cases — including those involving dangerous drugs like Depo-Provera.
We work on a contingency-fee basis, ensuring that you do not pay unless we secure compensation for you.
If you or a loved one has developed a brain tumor after using Depo-Provera, you may be eligible to seek compensation.
Contact TruLaw using the chat on this page to receive an instant case evaluation and determine whether you qualify to join others in filing a Depo-Provera lawsuit today.
Our Depo-Provera attorney at TruLaw is dedicated to supporting clients through the process of filing a Depo-Provera lawsuit.
With extensive experience in handling pharmaceutical litigation cases, Jessica Paluch-Hoerman provides personalized support and advocacy to clients who have suffered health issues after using this contraceptive medication.
Meet our lead Depo-Provera attorney:
At TruLaw, we believe financial concerns should never stand in the way of justice.
That’s why we operate on a contingency fee basis—with this approach, you won’t face any upfront costs for your legal representation.
Our fee is only collected if we are successful in securing compensation on your behalf.
This arrangement not only removes the financial risk of pursuing your case, it allows us to focus our resources on achieving a positive outcome in your case by:
Our investment in representing you demonstrates our unwavering commitment to seeking the compensation you deserve.
If you or a loved one experienced health complications after using Depo-Provera, you may be eligible to seek compensation.
Contact TruLaw using the chat on this page to receive an instant case evaluation and determine whether you qualify to join others in filing a Depo-Provera lawsuit today.
Patients filing lawsuits in the Depo-Provera multidistrict litigation (MDL) have reported numerous symptoms associated with meningioma brain tumors that developed after long-term use of the birth control injection.
These symptoms typically manifest as the slow-growing tumors press against brain tissue.
The common symptoms mentioned in the MDL include, but are not limited to:
Many plaintiffs report that these symptoms developed gradually over time, making early diagnosis challenging.
The MDL documentation notes that symptoms often worsen as tumors grow, with some patients requiring surgical intervention, craniotomies, and radiation therapy to address their condition.
The litigation focuses on claims that Pfizer failed to adequately warn U.S. patients about the link between Depo-Provera and meningiomas despite acknowledging this risk on product labels in other countries.
Persistent headaches often serve as the first warning sign of a meningioma in women who’ve used Depo-Provera.
These headaches typically intensify over time and may not respond to standard pain medications.
Vision disturbances appear in many patients as tumors press on the optic nerves.
Watch for blurry vision, double vision, peripheral vision loss, or temporary blindness episodes that come and go.
Cognitive changes including memory problems, difficulty concentrating, and confusion can develop gradually.
You might struggle with finding words, completing familiar tasks, or notice personality changes that others point out before you recognize them yourself.
Many women dismiss these early symptoms as stress, aging, or hormonal changes, delaying diagnosis.
Symptoms often worsen slowly as meningiomas typically grow at a rate of 1-2 millimeters per year, allowing tumors to reach substantial size before causing unmistakable problems.
Seizures, particularly in people with no prior history of epilepsy, represent a significant warning sign.
These can range from brief staring episodes to full-body convulsions requiring immediate medical attention.
Hearing changes, including progressive loss or persistent ringing in the ears (tinnitus), may signal tumors affecting auditory pathways.
Some patients describe a pulsating sound synchronized with their heartbeat.
Muscle weakness or numbness often affects one side of the body more than the other.
You might notice dropping objects, stumbling while walking, or difficulty with precise hand movements that worsen over time.
Loss of smell (anosmia) can be an early indicator of tumors near the front of the brain.
This symptom frequently goes unnoticed or gets attributed to allergies or sinus problems until other symptoms develop.
The location of the meningioma determines which symptoms appear first and most prominently.
Tumors near the skull base may cause different symptoms than those growing along the upper surface of the brain.
The active ingredient in Depo-Provera, medroxyprogesterone acetate (MPA), belongs to a class of hormones called progestogens.
Medical research shows these compounds can stimulate growth in certain brain tissues when present at high levels over extended periods.
Recent studies found women using Depo-Provera faced 5.6 times higher risk of developing meningiomas compared to non-users.
This study was conducted by EPI-PHARE Scientific Interest Group, a joint initiative of the French National Agency for Medicines and Health Products Safety and the French National Health Insurance, that tracked over 10,000 patients for eight years.
The tumors typically grow slowly, allowing them to substantially increase in size before causing noticeable symptoms.
Scientists first documented concerns about progestogens and brain tumor risk in small studies dating back to 2007, though these early findings received limited attention from regulators.
European health authorities added warning labels about potential meningioma risks to Depo-Provera packaging in 2018, nearly three years before similar warnings appeared on Canadian products.
US patients received no comparable notification during this period.
Pfizer updated prescribing information for US healthcare providers in January 2024, but many women who received Depo-Provera injections between 1992 and 2023 report they never learned about potential brain tumor risks from their doctors.
Despite evidence linking Depo-Provera to meningiomas, the FDA has not required a black box warning about brain tumor risks similar to the one issued for bone density loss in 2004.
Warning labels about meningioma risks have appeared on Depo-Provera packaging in Canada and the European Union for nearly a decade, yet similar warnings remain absent from U.S. product labeling.
Medical advocates argue the FDA should require stronger warnings about brain tumor risks, especially for women considering long-term use of the injectable contraceptive.
While the $2.17 million Canadian settlement in 2021 focused exclusively on bone density issues, current U.S. litigation centers primarily on meningioma brain tumor claims.
The first U.S. meningioma lawsuit was filed in October 2024 by a woman who had used Depo-Provera for approximately 17 years before developing a brain tumor requiring medical intervention.
These cases allege Pfizer knew or should have known about meningioma risks since at least 1983—nearly a decade before the FDA approved Depo-Provera for contraception—yet failed to properly investigate or disclose these risks to U.S. patients.
Legal experts anticipate potentially larger compensation in meningioma cases due to the severe nature of brain injuries and evidence suggesting deliberate withholding of risk information from U.S. consumers.
Seek medical attention right away if you develop headaches, vision changes, or other neurological symptoms after using Depo-Provera.
Early diagnosis can significantly improve treatment outcomes for meningiomas.
Call your primary care doctor first, who may refer you to a neurologist for specialized evaluation.
When making your appointment, mention your history of Depo-Provera use and ask specifically about meningioma concerns.
During your medical evaluation, doctors typically follow these diagnostic steps:
Be prepared to ask your doctor these specific questions:
For small tumors that aren’t causing severe symptoms, your doctor might recommend regular monitoring with follow-up MRI scans.
Don’t hesitate to seek a second opinion, especially if your symptoms persist despite negative initial test results.
Begin collecting evidence of your Depo-Provera use immediately. Contact your gynecologist’s office to request:
Your pharmacy can provide additional documentation, including:
Create a detailed symptom journal documenting:
Take photographs or videos of visible symptoms when possible, such as changes in facial movements or difficulties with coordination.
Include date stamps to establish a timeline.
Request copies of all diagnostic test results, including MRI and CT scan reports, even if initial results appear negative.
These baseline images may become important for comparison if symptoms progress.
Before speaking with insurance representatives or considering legal action, consult with an attorney who specializes in Depo-Provera litigation.
Most law firms handling these cases offer free consultations and can help determine if your medical documentation supports a potential claim.
Depo-Provera lawsuits are being filed by individuals across the country who developed meningiomas after using the contraceptive injection.
TruLaw is currently accepting clients for the Depo-Provera litigation against Pfizer.
A few reasons to choose TruLaw for your Depo-Provera lawsuit include:
If you or a loved one developed meningiomas after using Depo-Provera, you may be eligible to seek compensation.
Contact TruLaw using the chat on this page to receive an instant case evaluation that can determine if you qualify for the Depo-Provera litigation today.
The most common early symptoms include severe headaches and vision disturbances that worsen over time.
Recognizing cognitive changes, including memory problems and difficulty concentrating, may help identify issues related to a potential Depo-Provera brain tumor that develop gradually.
Women taking depo provera face 5.6 times higher risk of developing meningiomas compared to non-users.
This study was conducted by EPI-PHARE Scientific Interest Group, a joint initiative of the French National Agency for Medicines and Health Products Safety and the French National Health Insurance, and tracked over 10,000 patients for eight years.
Contact your primary care physician immediately and mention your history of prolonged depo provera use when scheduling an appointment.
Your doctor should evaluate you for blood clots and may order an MRI with contrast or refer you to a neurologist.
Meningiomas typically grow at a rate of 1-2 millimeters per year in patients who received the Depo-Provera shot, allowing tumors to reach substantial size before causing unmistakable problems.
This slow growth rate often means patients who used this injectable contraceptive Depo Provera may have symptoms that develop gradually and get overlooked.
Gather complete records showing when you used birth control shot and create a detailed symptom journal documenting when each symptom first appeared.
If you plan to file a Depo-Provera lawsuit, request copies of all diagnostic test results and medical records from your healthcare providers.
The Depo-Provera lawsuit resulted from many cases involving patients who experienced adverse effects from this medication.
Many patients with prolonged Depo-Provera exposure between 1992 and 2023 have contacted Depo-provera lawyers to discuss Depo-Provera claims after learning about the association with meningiomas through the Depo-Provera multidistrict litigation rather than from their healthcare providers.
Managing Attorney & Owner
With over 25 years of legal experience, Jessica Paluch-Hoerman is an Illinois lawyer, a CPA, and a mother of three. She spent the first decade of her career working as an international tax attorney at Deloitte.
In 2009, Jessie co-founded her own law firm with her husband – which has scaled to over 30 employees since its conception.
In 2016, Jessie founded TruLaw, which allows her to collaborate with attorneys and legal experts across the United States on a daily basis. This hypervaluable network of experts is what enables her to share the most reliable, accurate, and up-to-date legal information with our readers!
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Here, at TruLaw, we’re committed to helping victims get the justice they deserve.
Alongside our partner law firms, we have successfully collected over $3 Billion in verdicts and settlements on behalf of injured individuals.
Would you like our help?