Instant Case Decision
See if you qualify for a heartburn medicine (PPI) lawsuit and the right to potentially significant financial recovery.
The Heartburn Medication Instant Case Evaluator provides lawsuit qualification information and details regarding your situation.
1. Did you take heartburn medication?
2. Did you then develop kidney problems?
What are Proton Pump Inhibitors (PPI’s)?
Proton Pump Inhibitors, or better know as heartburn drugs, are designed to help people with heartburn, indigestion, GERD (acid reflux). They are the second-largest class of drugs sold in the United States (behind cholesterol regulators) with an estimated 15 million people prescribed PPIs in 2013 alone. Sales for heartburn medicine were $13.68 billion in 20016, which includes branded and generic drugs.
Nexium, manufactured by AstraZeneca, has been one of the top selling drugs in the U.S. with more than $6 billion in sales estimated by IMS Health in 2013. Prior to Nexium, AstraZeneca saw success with their drug Prilosec, but Prilosec went OTC (over the counter) in the summer of 2003, dropping the price and the profit for AstraZeneca. Critics have noted that the shortage of Prilosec in 2005 may have been planned. Nexium was approved in 2001, but started to see an increase in profit around the same time Prilosec was sold over the counter.Originally, Histamine H2 blockers were developed to stop the action of histamine on gastric H2 receptors, therefore decreasing gastric acidity. At this time, they were considered a medical breakthrough in treatment of Peptic Ulcer Disease. Since then, PPI’s has lessened the demand for this drug.
Who is affected by Heartburn?
More than 60 million Americans experience heartburn at least once a month and more than 15 million Americans experience heartburn daily. It is expected that these numbers will increase as a result of our aging population, since heartburn is more common among the elderly.
Individuals who get heartburn two or more times weekly may have gastroesophageal reflux disease (or GERD). GERD makes stomach acid flow up into the esophagus, which creates a burning. Nexium and other heartburn medicines are often prescribed for individuals who have been diagnosed with GERD or frequent heartburn although many critics note that changing eating habits and using over-the-counter medicines can be just as effective.
Heartburn Drugs Serve Three General Purposes
|1. Relieve symptoms of Gastroesophageal Reflux Disease (acid reflux)|
|2. Treat a peptic or stomach ulcer|
|3. Treat the harm caused to the lower esophagus due to acid reflux|
How Do Heartburn Drugs Work?
Heartburn medicines reduce the amount of stomach acid made by glands in the lining of your stomach.
In a more advanced explanation, heartburn drugs are converted to an active inhibitor and then bind covalently to a proton pump that inhibits it, all due to the acidic conditions in the parietal cells.
There are many heartburn drugs sold either by prescription or over the counter (OTC), they are also referred to as stomach acid drugs, acid reflux medicines and digestive disorder medicines.
Common Heartburn Medicines Include:
Side Effects of Heartburn Medicines
Recent journal articles and media attention have been on the links between heartburn medicines such as Nexium and the risk of chronic kidney disease (CKD). In addition to Kidney disease, Nexium and the other heart heartburn medicines have been linked to
Chronic Kidney Disease (CKD) Linked to Nexium and other Heartburn Medicines
In February of 2016, JAMA published the results from a study that showed people taking Prilosec and other proton pump inhibitors (PPI) may have a 20 to 50 percent increased risk of chronic kidney disease. The longer the heartburn medicine was taken, the greater the risk.
Chronic Kidney Disease involves the gradual loss of kidney function. CKD can progress to kidney failure, which is fatal unless a patient undergoes dialysis or a kidney transplant.
Should you file a heartburn drug lawsuit to protect your legal rights?
Did you use one of these medications?
Did you then develop problems with your kidneys?
Chronic Kidney Disease
Acute Interstitial Nephritis
Other Kidney Problems
If you answered yes to these two questions you should look into your legal rights. Fill out our Secure Heartburn Instant Case Evaluation if you believe you may need to protect your legal rights.
View Your Heartburn Drug Case Analysis Now!
Instant, Secure, No cost/No obligation Analysis of Your PPI Lawsuit
Did your heartburn/indigestions medicine cause your kidneys to fail?
You should look into your legal rights. New studies are showing evidence of an alarming relationship between use of these medications (known generically as Proton Pump Inhibitors) and kidney problems, including kidney failure requiring dialysis. This is a serious problem. The Heartburn Medicine lawyers at TruLaw and its partners are actively talking to individuals who have experienced side effects from heartburn drugs and are currently considering protecting their legal rights.
To instantly find out if you qualify for a lawsuit and to protect your legal rights fill out our Secure Heartburn Medicine Instant Case Evaluation.
Recent Heartburn Medication News
Heartburn Drug Side Effects – A Timeline
In February of 2016, the Journal of American Nephrology published a study called “Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD”.
Using the Department of Veteran Affairs national databases, they were able to compile a list of patients to use for the study. There were approximately 173,321 using a proton pump inhibitor, and 20,270 people assigned to H2 antagonists as a control group.
In the whole study, only 0.2 percent of patients developed end stage kidney failure. However, the risk of developing it was 96 percent higher than users of H2 blockers.
Exposure to PPI use played a factor in the risk of developing kidney failure. If you have been using a PPI for more than 30 days, there is a higher graded risk of renal malfunction.
Overall, results from this study suggested that PPI use is associated with an increased risk of incident for Chronic Kidney Disease, CKD progression and End-Stage Renal Disease.
Unfortunately, this is not the only study noting these frightening claims. A study ran by JAMA Internal Medicine titled, “Atherosclerosis Risk in Communities” found similar results.
Between 1996 to 2011, 10,482 participants had baseline visits. The data was analyzed in 2015 from May to October.
Among the participants, the mean age was 63 and 43.9 percent were male. Participants who were white, obese and taking antihypertensive medication were most often using PPI’s.
As mentioned before, the results were grave. JAMA Internal Medicine concluded that proton pump inhibitor use is associated with an increased risk of incident of Chronic Kidney Disease. They believe that further research should be done to evaluate if reducing PPI use reduces the incident of CKD.