How long do side effects last after stopping Depo-Provera?

Most side effects begin to diminish within 3-6 months after your last injection. However, some effects related to medroxyprogesterone injections may persist longer. Menstrual irregularities typically resolve within a year, while bone density often improves gradually over 2-3 years. Meningiomas related to hormone exposure may continue to grow even after discontinuation, requiring ongoing monitoring.

Which Depo Provera side effects are reversible vs. permanent?

Most Depo Provera side effects are reversible, including: <ul> <li>Menstrual irregularities</li> <li>Weight gain</li> <li>Mood changes</li> <li>Bone density loss (in most cases)</li> </ul> However, meningioma tumors generally require medical intervention and may not regress spontaneously after stopping the medication. In rare cases, very severe bone density loss might not fully reverse.

How common are serious long-term side effects?

Serious side effects occur in a minority of users. Research shows Depo-Provera users experience bone density loss at the hip of approximately 1.12% per year compared with 0.05% for non-users. The FDA has required a black box warning about this potential bone density loss. The risk of meningioma appears to be about 5.55 times higher in long-term users compared to non-users, though the absolute risk remains relatively low.

Can supplements reduce side effect risks?

Calcium and vitamin D supplements may help support bone health while using Depo-Provera. However, no supplements have been proven to reduce the risk of other side effects, including meningioma development. Always consult a healthcare provider before starting any supplement regimen.

What is the percentage risk increase for meningioma with long-term use?

A March 2024 study found that users of Depo-Provera for one year or more faced a 5.55-fold increased risk of developing meningiomas requiring surgery. Another study confirmed 53% greater odds of developing meningioma in users compared to non-users. The risk appears dose-dependent, meaning longer use and higher cumulative doses further increase risk.

Are meningiomas cancerous?

Most meningiomas (over 90%) are non-cancerous (benign). However, even benign meningiomas can cause serious health issues by pressing on brain tissue, nerves, or blood vessels. About 1-2% of meningiomas are classified as atypical, and less than 1% are malignant.

How are meningiomas typically treated?

The best approach depends on tumor size, location, and individual health factors. Meningioma treatment options typically include, but are not limited to: <ul> <li>Observation with regular imaging for small, asymptomatic tumors</li> <li>Surgical removal for larger or symptomatic tumors</li> <li>Radiation therapy when surgery isn’t possible or complete</li> <li>Medication therapy in certain cases</li> </ul>

Should all long-term users get brain scans?

Currently, routine brain scans aren’t recommended for all users without symptoms. However, prompt medical evaluation is advised for persistent headaches, vision changes, or other neurological symptoms after receiving medroxyprogesterone injections. Women who used Depo-Provera for one year or more might discuss screening options with their healthcare provider, as research shows risk increases after just one year of use.

How do I know if I qualify for a Depo-Provera lawsuit?

TruLaw can provide an immediate case evaluation through the chat found on this page. You may qualify for a Depo-Provera lawsuit if you: <ul> <li>Used Depo-Provera for an extended period (typically 1+ years)</li> <li>Were diagnosed with a meningioma brain tumor</li> <li>Received inadequate warnings about this potential risk</li> </ul>

What is the time limit for filing a Depo shot lawsuit claim?

Statutes of limitations vary by state, typically ranging from 1-3 years from either: <ul> <li>The date of diagnosis, or</li> <li>The date you discovered (or reasonably should have discovered) the connection between Depo-Provera and your health condition</li> </ul> However, this can differ on a case by case basis – for that reason, it’s important to discuss the details of your situation with an experienced Depo Provera attorney. They can help you understand how the statute of limitations will impact your case and ensure you do not miss any important deadlines. If you or a loved one developed a meningioma after using Depo-Provera, you may be eligible to seek compensation. Contact TruLaw using the chat on this page to receive an instant case evaluation and determine whether you qualify to join others in filing a Depo-Provera lawsuit today.

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May 21, 2025

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